Agent Name

Styrene-7,8-oxide

Alternative Name

Styrene oxide

CAS Number

96-09-3

Formula

C8-H8-O

Major Category

Plastics & Rubber

Synonyms

Styrene oxide; 1,2-Epoxy-1-phenylethane; 1,2-Epoxyethylbenzene; 1-Phenyl-1,2-epoxyethane; 1-Phenyloxirane; 2-Phenyloxirane; Benzene, (1,2-epoxyethyl)-; Benzene, (epoxyethyl)-; EP-182; Epoxyethyl benzene; Epoxyethylbenzene; Epoxystyrene; Fenyloxiran [Czech]; Oxirane, phenyl-; Phenethylene oxide; Phenyl oxirane; Phenylethylene oxide; Phenyloxirane; Styrene epoxide; Styrene oxide; Styryl oxide; [ChemIDplus]

Category

Epoxides

Description

Colorless to light yellow liquid; [Hawley] Pleasant, sweet odor; [HSDB] Faintly yellow-green clear liquid; [MSDSonline]

Sources/Uses

Used as a reactive diluent for epoxy resins, a curing agent for polyesters and polyurethanes, a stabilizer (hydraulic fluids, chlorinated cleaning compounds, petroleum distillates, dielectric fluids, and acid-sensitive polymers and copolymers), and a lubricant for acetal polymers; [HSDB]

Comments

A skin and eye irritant; Inhalation of high concentrations may cause CNS depression; [ICSC] Toxic by ingestion and inhalation; [Hawley] Repeated exposure may lead to skin sensitization; [HSDB] May cause skin burns, sensitization, liver injury, and CNS depression; [CAMEO] An eye irritant and lachrymator; May cause CNS depression; Targets the CNS and liver; [MSDSonline]

Exposure Assessment
Vapor Pressure

0.3 mm Hg

Lethal Concentration

LCLo (rat) = 500 ppm/4h

Explanatory Notes

Flash point = 76 deg C; [ICSC] Odor low 0.3093 mg/m3; Odor high 1.9640 mg/m3; [HSDB] See "2018 Notice of Intended Changes." [TLVs and BEIs]

Adverse Effects
Skin Sensitizer

Yes

Lacrimator

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Probable Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: