Agent Name

1,4-Benzenediamine sulfate

CAS Number

16245-77-5

Formula

C6-H8-N2.H2-O4-S

Major Category

Nitrogen Compounds

Synonyms

p-Phenylenediamine sulfate; Benzene-1,4-diammonium sulphate; [ChemIDplus]

Category

Amines, Aromatic

Description

White to off-white solid; [MSDSonline]

Sources/Uses

Not commercially available; [HSDB]

Comments

Emergency treatment: "Paraphenylenediamine"; In sensitized individuals, paraphenylenediamine may cause allergic contact dermatitis following application as a hair dye and asthma following inhalation; Following ingestion, can cause angioneurotic edema, methemoglobinemia, acute tubular necrosis, and hepatotoxicity; An adult died after ingestion of 3 grams of p-phenylenediamine; Another adult who ingested 1800 mg developed angioneurotic edema and acute renal failure; [HSDB] See "p-Phenylenediamine."

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: