Agent Name

t-Butylhydroquinone

Alternative Name

TBHQ

CAS Number

1948-33-0

Formula

C10-H14-O2

Major Category

Other Classes

Synonyms

1,4-Benzenediol (1,1-dimethylethyl)-; 1,4-Benzenediol, 2-(1,1-dimethylethyl)-; 2-(1,1-Dimethylethyl)-1,4-benzenediol; 2-t-Butylhydroquinone; 2-tert-Butyl(1,4)hydroquinone; 2-tert-Butyl-1,4-benzenediol; 2-tert-Butylhydroquinone; Banox 20BA; Hydroquinone, t-butyl-; Hydroquinone, tert-butyl-; MTBHQ; Mono-tert-butylhydroquinone; Mono-tertiarybutylhydroquinone; Sustane; TBHQ; Tenox TBHQ; t-Butyl hydroquinone; tert-Butyl-1,4-benzenediol; tert-Butylhydrochinone ; tert-Butylhydroquinone; tertiary-Butylhydroquinone; Butylhydroquinone, tert-; [ChemIDplus] UN3077

Category

Phenols

Description

White to light tan solid; [HSDB] Tan powder; [MSDSonline]

Sources/Uses

Used as antioxidant for fats and oils (approved for use in foods); [HSDB] Used at concentrations of 0.1 to 1.0% in cosmetics; Also used to prevent rancidity in food at concentrations of 0.02%; [REPROTOX]

Comments

Causes ataxia in inhalation studies and changes in liver weight in feeding studies of laboratory animals; [RTECS] Not likely to be embryotoxic in humans based on studies of rats exposed to 0.5% in the diet; [REPROTOX] A skin and eye irritant; [CAMEO] Skin sensitization has been reported in cosmetics and cutting oils; [Kanerva, p. 1763] An irritant; [MSDSonline] See "Hydroquinone."

Exposure Assessment
Lethal Concentration

LCLo (rat) = 2,900 mg/m3/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Environmentally hazardous substances, solid, n.o.s."

Adverse Effects
Skin Sensitizer

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: