Agent Name

Taxine

CAS Number

12607-93-1

Formula

C37-H51-N-O10

Major Category

Biological Agents

Synonyms

Taxin [German]; [ChemIDplus]

Category

Plant Toxins

Description

Solid; [Merck Index]

Sources/Uses

Alkaloid mixture found in needles and berries of Taxus baccata L., Taxaceae (yew tree); [Merck Index]

Comments

Emergency treatment: "Plants- taxus"; In 7269 poisoning cases, 92.5% of patients had no adverse effects. Estimated lethal dose is 50-100 grams of the needles. One chewed berry may be lethal for a child. [HSDB] Symptoms of fatal poisoning include GI irritation and cardiac and respiratory failure; [Merck Index] Causes AV block, wide QRS, and hypotension; [Olson, p. 392]

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