Agent Name

Tetra-n-butyltin

CAS Number

1461-25-2

Formula

C16-H36-Sn

Major Category

Metals

Synonyms

Stannane, tetrabutyl-; Tetra-n-butylcin [Czech]; Tetrabutylstannane; Tetrabutyltin; Tin, tetrabutyl-; [ChemIDplus] UN2788

Category

Tin Compounds, Organic

Description

Colorless or slightly yellow liquid; [Hawley] Colorless liquid; [MSDSonline]

Sources/Uses

Used as a silicone additive, lubricant, fuel additive, polymerization catalyst, and hydrochloric acid scavenger; [Hawley]

Comments

In lethal dose animal studies, causes somnolence (general depressed behavior); Oral LD50 (rat) = 1268 mg/kg; Intravenous LD50 (rat) = 48 mg/kg; [ChemIDplus] An irritant; [Hawley] An irritant; May cause skin and respiratory sensitization after prolonged contact; [MSDSonline] See "ORGANOMETALS." See "Tin, organic compounds."

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.1 mg/m3, as Sn

STEL (ACGIH)

0.2 mg/m3, as Sn

PEL (OSHA)

0.1 mg/m3, as Sn

MAK

0.02 mg/m3, inhalable fraction

IDLH (NIOSH)

25 mg/m3, as Sn

Vapor Pressure

0.0048 mm Hg

Lethal Concentration

LC50 (mice) = 142 mg/m3

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organotin compound, liquid, n.o.s." Organic tin compounds have a "skin" designation and are classified as "A4" (Not classifiable as human carcinogen); [ACGIH]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Processes

Industrial Processes with risk of exposure: