Agent Name

Tetrabromodiphenyl ethers

CAS Number

40088-47-9

Formula

C12-H6-Br4-O

Major Category

Other Classes

Synonyms

Tetrabromobiphenyl ether; Tetrabromodiphenyl ether; Tetrabromodiphenyl oxide; Benzene, 1,1'-oxybis-, tetrabromo deriv.; Diphenyl ether, tetrabromo derivative; [ChemIDplus]

Category

Halogenated Polyaromatics

Description

Composition of commercial Tetrabromodiphenyl ether: 7.6% polybrominated diphenyl ethers, 41-41.7% tetrabromodiphenyl ether, 44.4-45% pentabromodiphenyl ether and 6-7% hexabromodiphenyl ether." [HSDB]

Sources/Uses

Used as flame retardants, typically at 3 to 12% of the product; Workers may be exposed during the weighing and mixing of flame retardant resins and polymers; [Reference #1]

Comments

The primary health concerns of polybrominated flame retardants are their potential to act as carcinogens, endocrine disruptors, and neurodevelopmental toxicants; Polybrominated diphenyl ethers (PBDPEs) may have effects on the liver and possibly the thyroid; The majority of the absorbed tetrabromdiphenyl ether is stored in adipose tissue; Adverse effects may include lowering of the serum and total T4 thyroid hormone; [Reference #1] See "Phenyl ether, vapor."

Reference Link

NICNAS: Polybrominated Flame Retardants - 2001

Exposure Assessment
Reference Link

An Exposure Assessment of Polybrominated Diphenyl Ethers (PBDE) (Final) US EPA - 2010

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.