Agent Name

Tetrahydrophthalic anhydride

CAS Number

85-43-8

Formula

C8-H8-O3

Major Category

Plastics & Rubber

Synonyms

1,2,3,6-Tetrahydrophthalic acid anhydride; 1,2,3,6-Tetrahydrophthalic anhydride; 1,3-Isobenzofurandione, 3a,4,7,7a-tetrahydro-; 4-Cyclohexene-1,2-dicarboxylic acid anhydride; 4-Cyclohexene-1,2-dicarboxylic anhydride; Anhydrid kyseliny tetrahydroftalove [Czech]; Butadiene-maleic anhydride adduct; Maleic anhydride adduct of butadiene; Memtetrahydro phtalic anhydride; Phthalic anhydride, 1,2,3,6-tetrahydro-; Rikacid TH; THPA; Tetrahydroftalanhydrid [Czech]; Tetrahydrophthalic acid anhydride; delta(4)-Tetrahydrophthalic anhydride; delta(sup 4)-Tetrahydrophthalic anhydride; delta-(sup4)-Tetrahydrophthalic anhydride; [ChemIDplus] UN2698

Category

Acid Anhydrides, Cyclic

Description

White solid; [ICSC]; [CHEMINFO] Clear colorless to light yellow liquid; [CAMEO]

Sources/Uses

Used as an intermediate for light-colored alkyds, polyesters, plasticizers, adhesives, and pesticides; Also used as a hardener for resins, an anti-scorching agent in the rubber industry, and to make paints, lacquers, and varnishes; [HSDB]

Comments

Decomposed by hot surfaces or flames forming corrosive vapors; Reacts with water evolving heat and tetrahydrophthalic acid; A skin, eye, and respiratory tract irritant; May cause skin sensitization and asthma after prolonged contact; [ICSC] Corrosive to skin, eye, and respiratory tract; [HSDB] Reacts exothermically with water producing tetrahydrophthalic acid; A strong skin, eye, and mucous membrane irritant; Corrosive to skin; [CAMEO] May be irritating or corrosive to eyes, based on animal studies; [CHEMINFO] Corrosive to eyes; May cause skin and respiratory sensitization after prolonged contact; [eChemPortal: ERMA; ESIS] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis and pulmonary edema; [MSDSonline]

Exposure Assessment
Vapor Pressure

0.05 mm Hg

Lethal Concentration

LC (rat) > 294 mg/m3

Adverse Effects
Asthma

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: