Agent Name

ACID ANHYDRIDES

Alternative Name

CLASS

Major Category

Plastics & Rubber

Synonyms

CLASSES

Category

Acid Anhydrides, Cyclic

Sources/Uses

The acid anhydrides are used primarily as curing agents for alkyl and epoxy resins. [Rom, p. 1213] They are also one of the basic building blocks of polyesters. [Sullivan, p. 473]

Comments

An acid anhydride is a chemical compound that can form the acid when united with a molecule of water, e.g., from phthalic anhydride to phthalic acid. [Hawley] Acid anhydrides cause immunologic, occupational contact urticaria. [Kanerva, p. 219] Phthalic anhydride and trimellitic anhydride are in the NIOSH Pocket Guide. Six other acid anhydrides are listed in "Agents Causing Occupational Asthma with Key References" by Chan-Yeung & Malo [Malo] These six are tetrachlorophthalic anhydride, pyromellitic dianhydride, methyl tetrahydrophthalic anhydride, himic anhydride, chlorendic anhydride, and maleic anhydride. See "Trimellitic anhydride."

Reference Link

INCHEM CICAD: Cyclic Acid Anhydrides - 2009

Adverse Effects
Asthma

Yes

Links to Other NLM Databases
Toxicity Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: