Agent Name

Tolylfluanid

CAS Number

731-27-1

Formula

C10-H13-Cl2-F-N2-O2-S2

Major Category

Pesticides

Synonyms

1,1-Dichloro-N-((dimethylamino)sulfonyl)-1-fluoro-N-(4-methylphenyl)methanesulfenamide (9CI); BAY 49854; BAY 5212; BAY 5712a; Bayer 49854; Bayer 5712a; Dichlofluanid-methyl; Euparen M; KUE 13183b; Methanesulfanenamide, 1,1-dichloro-N-((dimethylamino)sulfonyl)-1-fluoro-N-(4-methylphenyl)-; N'-Dichlorofluoromethylthio-N,N-dimethyl-N'-(4-tolyl)sulfamide; N,N-Dimethyl-N'-(4-tolyl)-N'-(dichlorfluormethylthio)-sulfamid [German]; N,N-Dimethyl-N-(4-tolyl)-N-(dichlorofluor-methylthio)-sulfamide; N-Dichlorofluoromethanesulphenyl-N',N'-dimethyl-N-p-tolylsulphamide; N-Dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulphamide; Tolylfluanide [ISO-French]; Dichloro-N-((dimethylamino)sulphonyl)fluoro-N-(p-tolyl)methanesulphenamide; Sulfamide, N-((dichlorofluoromethyl)thio)-N',N'-dimethyl-N-(p-tolyl)-; [ChemIDplus]

Category

Fungicides

Description

Colorless odorless solid; [HSDB] White to pale yellow crystalline solid; [MSDSonline]

Sources/Uses

Used as fungicide to protect grapes, vegetables, and ornamentals; Not currently registered with the EPA for use in the US; Manufactured in Germany for use outside the US; Not commercially produced in the US; [HSDB] A foliar fungicide for fruits, vegetables, and hops; [Reference #2]

Comments

Likely to be carcinogenic to humans; Target organs are bones & teeth, liver, and thyroid; [Reference #1] Irritating to the skin and has sensitizing properties; Target organs after acute exposure are liver, kidney, and thyroid gland; Causes severe respiratory irritation after inhalation of particles < 50 microns; Not genotoxic; Not carcinogenic; No evidence of reproductive or CNS toxicity; [Reference #2] A skin, eye, and respiratory tract irritant; May cause skin sensitization; [eChemPortal: ESIS] An irritant; [MSDSonline]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
Vapor Pressure

1.5E-6 mm Hg

Lethal Concentration

LC50 (rat) = 300 mg/m3/4h

Reference Link

EFSA: Tolyfluanid - 2005

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: