Agent Name

Tonalid

CAS Number

21145-77-7; 1506-02-1

Formula

C18-H26-O

Major Category

Other Classes

Synonyms

2'-Acetonaphthone, 5',6',7',8'-tetrahydro-3',5',5',6',8',8'-hexamethyl-; AHMT; AHMT (perfume); AHTN; Musk tonalid; Tentarome; Tetralide; Tonalide; 1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one; Ethanone, 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)-; [ChemIDplus]

Category

Aromatic Ketones

Description

Solid with an odor of musk; [HSDB]

Sources/Uses

Used as fragrance for cosmetics, detergents, fabric softeners, household cleaning products, and air fresheners; [HSDB]

Comments

A mild eye irritant, based on animal studies; [CHEMINFO] Causes liver injury in high-dose animal experiments; [RTECS] May be safely used as a fragrance in cosmetics up to 12%; [European Commission] Included in list of "fragrance substances with negative human data, i.e. patch tests of patients with suspected contact allergy to fragrance ingredients which yielded negative results."; [ToxPlanet: EC: Scientific Committee on Consumer Safety: Fragrance allergens in cosmetic products (2011)] May cause irritation; [MSDSonline]

Exposure Assessment
Vapor Pressure

0.000512 mm Hg

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Other Information

No other related information on this agent was found.