Agent Name

Triazophos

CAS Number

24017-47-8

Formula

C12-H16-N3-O3-P-S

Major Category

Pesticides

Synonyms

1-Phenyl-1,2,4-triazolyl-3-(O,O-diethylthionophosphate); 1-Phenyl-3-(O,O-diethyl-thionophosphoryl)-1,2,4-triazole; HOE 2960; HOE 2960 OJ; Hostathion; O,O-Diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl) phosphorothioate (8CI)(9CI); O,O-Diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl)phosphorothioate; Phosphorothioic acid, 0,0-diethyl 0-(1-phenyl-1H-1,2,4-triazol-3-yl) ester; Triazofosz (Hungarian); Triazofos; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Light brown liquid; mp = 0-5 deg C; [Merck Index] Yellowish liquid; [HSDB]

Sources/Uses

Used as broad spectrum insecticide and acaricide for fruit and cereals; [HSDB]

Comments

A cholinesterase inhibitor; Can be absorbed through skin; [CAMEO] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Restricted

Not registered with the EPA for use as pesticide in the US; [CAMEO] Banned in the EU for use as a biocide and agricultural insecticide; [eChemPortal: ESIS]

Reference Link

INCHEM JMPR: Triazophos - 2002

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

2.9E-6 mm Hg

Lethal Concentration

LC50 (rat) = 450 mg/m3/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: