Agent Name

Vinyl acetate

CAS Number

108-05-4

Formula

C4-H6-O2

Major Category

Other Classes

Synonyms

1-Acetoxyethylene; Acetate de vinyle [French]; Acetic acid vinyl ester; Acetic acid, ethenyl ester; Acetic acid, ethylene ether; Acetoxyethene; Ethanoic acid, ethenyl ester; Ethenyl acetate; Ethenyl ethanoate; Octan winylu [Polish]; Vinile (acetato di) [Italian]; Vinyl A monomer; Vinyl acetate; Vinyl acetate H.Q.; Vinyl acetate monomer; Vinyl ethanoate; Vinylacetaat [Dutch]; Vinylacetat [German]; Vinylacetate; Vinyle (acetate de) [French]; Vinylester kyseliny octove [Czech]; Zeset T; [ChemIDplus] UN1301

Category

Esters, Other

Description

Colorless liquid with a pleasant, fruity odor. [Note: Raw material for many polyvinyl resins.]; [NIOSH]

Sources/Uses

Used in the production of polyvinyl acetate emulsions and polyvinyl alcohol; [ACGIH]

Comments

Vinyl acetate caused respiratory irritation in monomer production workers. Experimental animals suffer liver injury in feeding studies and central nervous system depression in inhalation studies. [ACGIH] A lachrymator; [CHEMINFO] May cause skin redness and blisters; A skin, eye, and respiratory tract irritant; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

10 ppm

STEL (ACGIH)

15 ppm

Vapor Pressure

90.2 mm Hg

Odor Threshold Low

0.11 ppm

Odor Threshold High

0.4 ppm

Lethal Concentration

LC50 (rat) = 11,400 mg/m3/4h

Explanatory Notes

Detection odor threshold from AIHA (mean = 0.12 ppm); Flash point = -8 deg C;

Half Life

Whole body (animal studies): less than 6 hours; [TDR, p. 1218]

Reference Link

ATSDR - ToxFAQs - Vinyl Acetate

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Lacrimator

Yes

Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

IARC Carcinogen

Possible Carcinogen

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: