Agent Name

Vinyl acetate

CAS Number

108-05-4

Formula

C4-H6-O2

Major Category

Other Classes

Synonyms

1-Acetoxyethylene; Acetate de vinyle [French]; Acetic acid vinyl ester; Acetic acid, ethenyl ester; Acetic acid, ethylene ether; Acetoxyethene; Ethanoic acid, ethenyl ester; Ethenyl acetate; Ethenyl ethanoate; Octan winylu [Polish]; Vinile (acetato di) [Italian]; Vinyl A monomer; Vinyl acetate; Vinyl acetate H.Q.; Vinyl acetate monomer; Vinyl ethanoate; Vinylacetaat [Dutch]; Vinylacetat [German]; Vinylacetate; Vinyle (acetate de) [French]; Vinylester kyseliny octove [Czech]; Zeset T; [ChemIDplus] UN1301

Category

Esters, Other

Description

Colorless liquid with a pleasant, fruity odor. [Note: Raw material for many polyvinyl resins.]; [NIOSH] Polymerizes when exposed to light; [ACGIH]

Sources/Uses

Used in the production of polyvinyl acetate emulsions, acrylic fiber, and polyvinyl alcohol; Occupational exposure occurs in production workers, painters, and floor layers; [ACGIH]

Comments

Vinyl acetate causes eye and respiratory irritation in production workers. Experimental animals show minor elevation of liver function tests after IP injection and central nervous system depression after inhalation; [ACGIH] A lachrymator; [CHEMINFO] May cause skin redness and blisters; A skin, eye, and respiratory tract irritant; [ICSC] Vinyl acetate, stabilized (UN1301) has warning of explosive polymerization; [ERG 2016]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

10 ppm

STEL (ACGIH)

15 ppm

Vapor Pressure

115 mm Hg

Odor Threshold Low

0.36 ppm

Odor Threshold High

0.5 ppm

Lethal Concentration

LC50 (rat) = 3680 ppm/4h

Explosive Polymerization

Yes

Explanatory Notes

Reported odor thresholds; [ACGIH]; Flash point = -8 deg C, closed cup; [ACGIH]

Half Life

Whole body (animal studies): less than 6 hours; [TDR, p. 1218]

Reference Link

ATSDR - ToxFAQs - Vinyl Acetate

Adverse Effects
Lacrimator

Yes

Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

IARC Carcinogen

Possible Carcinogen

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: