Agent Name

Triethylene glycol monoethyl ether

Alternative Name

TEGEE

CAS Number

112-50-5

Formula

C8-H18-O4

Major Category

Solvents

Synonyms

2-(2-(2-Ethoxyethoxy)ethoxy)ethanol; 3,6,9-Trioxaundecan-1-ol; Dowanol TE; Ethoxytriethylene glycol; Ethoxytriglycol; Ethyltriglycol; Poly-Solv TE; Triethylene glycol ethyl ether; Triglycol monoethyl ether; Ethanol, 2-(2-(2-ethoxyethoxy)ethoxy)-; [ChemIDplus] TGEE; [eChemPortal: SIDSUNEP]

Category

Glycol Ethers (E Series)

Description

Colorless hygroscopic liquid; [ICSC] Odorless; [HSDB]

Sources/Uses

Used as raw material for hydraulic brake fluids; Also used in coatings, printing inks, specialty chemicals, cleaning products, cutting oils, deicing agents, antisudsing agent for finely powdered materials, and food contact plastics (plasticizer); [HSDB] 95% used to make hydraulic brake fluid; [Reference #1]

Comments

In lethal-dose studies, causes congestion of kidneys and liver; One of 5 male rats exhibited testicular effects that were thought to be unrelated to treatment; No developmental toxicity in rats receiving 1000 mg/kg/day; Not expected to be genotoxic; [Reference #1] Defats the skin; [ICSC] A skin and mild eye irritant, based on animal studies; [eChemPortal: SIDSUNEP] May cause irritation; [MSDSonline] See "GLYCOL ETHERS."

Reference Link

OECD SIDS: 2-(2-(2-Ethoxyethoxy)ethoxy)ethanol - 1996

Exposure Assessment
Vapor Pressure

0.00224 mm Hg

Lethal Concentration

LC50 (rat) > 50,000 mg/m3/4h

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: