Agent Name

Trimethyl phosphate

CAS Number

512-56-1

Formula

C3-H9-O4-P

Major Category

Other Classes

Synonyms

O,O,O-Trimethyl phosphate; Phosphate, trimethyl-; Phosphoric acid, trimethyl ester; TMP; TMPA; TMPO; Trimethoxyphosphine oxide; Trimethyl orthophosphate; Trimethylfosfat [Czech]; [ChemIDplus]

Category

Organophosphates, Other

Description

Clear liquid; [Hawley]

Sources/Uses

Used as a gasoline additive, methylating agent, flame-resistant solvent for paints and polymers, catalyst in polymers and resins, and to make polymethyl polyphosphates; [HSDB]

Comments

Danger of cutaneous absorption; Carcinogenicity in man cannot be assessed conclusively because of insufficient data (Group 3B); "Germ cell mutagens that have shown to increase the mutant frequency in the progeny of exposed mammals." [MAK] A skin, eye, and respiratory tract irritant; Chronic or repeated exposure may cause flaccid paralysis and genetic damage; [ICSC] An irritant; Targets CNS; [MSDSonline]

Exposure Assessment
Explanatory Notes

Flash point = 107 deg C; [ICSC] VP = 1.0 mm Hg at 78.8 deg F; [CAMEO]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: