Agent Name

Tri(2-butoxyethyl) phosphate

CAS Number

78-51-3

Formula

C18-H39-O7-P

Major Category

Other Classes

Synonyms

2-Butoxyethanol, phosphate; Ethanol, 2-butoxy-, phosphate (3:1); KP 140; Kronitex KP-140; Phosflex T-BEP; Phosphoric acid, tributoxyethyl ester; Phosphoric acid, tris(2-butoxyethyl) ester; TBEP; Tri(2-butoxyethanol) phosphate; Tri(2-butoxyethanol)phosphate; Tributoxyethyl phosphate; Tributyl cellosolve phosphate; Tris(2-butoxyethyl) phosphate; Tris(butoxyethyl) phosphate; Tris-(2-butoxyethyl)fosfat [Czech]; [ChemIDplus]

Category

Organophosphates, Other

Description

Slightly yellow liquid with a sweetish odor; [HSDB]

Sources/Uses

Used as a plasticizer for resins and elastomers, in floor finishes and waxes, as a flame retardant, as a plasticizer for rubber stoppers in blood specimen containers, and as a fire-resistant and light-stable plasticizer for products intended for food contact; Occupational exposure is likely to be by skin absorption during production and from floor polishes; [HSDB] Used as solvent for resins, a viscosity modifier in plastisols, and an antifoam agent for synthetic rubber, plastics, and lacquers; [INCHEM]

Comments

Irritating to skin and eyes; The liver is the target organ in high-dose animal studies; Has anticholinesterase action at lethal doses; Skin absorption is expected to be low; No effect on neuropathy target esterase (NTE), but cholinesterases were inhibited in treated hens; [HSDB] An irritant; [MSDSonline]

Reference Link

INCHEM: Flame Retardants (EHC 218 - 2000)

Exposure Assessment
Vapor Pressure

2.5E-8 mm Hg

Lethal Concentration

LC (rat) > 600 mg/m3/6h

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: