Agent Name

Trisodium nitrilotriacetate

CAS Number

5064-31-3

Formula

C6-H9-N-O6.3Na

Major Category

Other Uses

Synonyms

N,N-Bis(carboxymethyl)glycine, trisodium salt; Nitrilotriacetic acid sodium salt; Acetic acid, nitrilotri-, trisodium salt; Cheelox NTA-14, Na3; Chemcolox 365 Powder; Glycine, N,N-bis(carboxymethyl)-, trisodium salt; Hampshire NTA; Hampshire NTA 150; Masquol NP 140; NTA trisodium salt; Nitrilotriacetate trisodium salt; Nitrilotriacetic acid trisodium salt; Nitrilotriacetic acid, trisodium salt; NTANa3; Sodium nitrilotriacetate; Syntron A; Trilon A; Trisodium 2,2',2''-nitrilotriacetate; Trisodium N,N-bis(carboxymethyl)glycinate; Trisodium NTA; Trisodium aminotriacetate; Trisodium nitrilotriacetic acid; Versene NTA 150; Versene NTA 335; [ChemIDplus]

Category

Chelating Agents

Description

White solid; [ICSC] Colorless or white solid; Slightly hygroscopic; [CHEMINFO]

Sources/Uses

Used as chelating agent in bleaching and as a sequestrant builder; Also used in tanning, synthetic rubber, textiles, pharmaceuticals, low phosphate and phosphate-free detergents, and in boiler-water treatment; [HSDB] Used for extraction, refining, and processing of metals; in the paper-pulp-board industry; and as an additive to construction materials; [IUCLID]

Comments

A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Possible human carcinogen; [ICSC] A skin, eye, nose, and throat irritant; Not sensitizing to human skin; High-dose feeding produces lesions of the urinary tract in mice and kidney lesions in rats; No evidence of reproductive or developmental toxicity in rats or rabbits; Emergency treatment: "Oxalic acid"; Oxalic acid is an irritant that, after ingestion, may cause kidney damage, hypocalcemia, and hepatic necrosis; [HSDB] An eye irritant; [eChemPortal: ESIS] Not irritating to rabbit or human skin; Irritating to rabbit eyes; Nephrotoxic in rats; [IUCLID] Mutagenic, tumorigenic, and toxic to reproduction; Causes changes in liver and bladder weights, erythrocyte count, and renal tubules in repeated dose studies of rats; [RTECS] May cause skin and eye irritation; Harmful if swallowed; [Aldrich MSDS] See "Nitrilotriacetic acid."

Exposure Assessment
Vapor Pressure

8.08E-10 mm Hg

Lethal Concentration

LC50 (rat) > 5,000 mg/m3/4h

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

IARC Carcinogen

Possible Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: