Agent Name

Pentaborane

CAS Number

19624-22-7

Formula

B5-H9

Major Category

Toxic Gases & Vapors

Synonyms

Pentaboron nonahydride; [NIOSH]

Category

Hydrides

Description

Colorless liquid with a pungent odor like sour milk; [NIOSH]

Sources/Uses

Pentaborane has been used as a rocket fuel. [ACGIH]

Comments

Workers accidentally exposed to pentaborane vapor experienced central nervous system effects at lower doses and tremors and seizures at higher doses. [ACGIH] A severe irritant of the eyes and respiratory tract; [ICSC] In one industrial accident with a fatality, patients had elevated liver enzymes and rhabdomyolysis. [HSDB] (Rhabdomyolysis is muscle tissue injury with release of myoglobin into the bloodstream and often associated kidney damage.)

Reference Link

NIOSH: Occupational Health Guideline for Pentaborane

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TIH

Yes

TLV (ACGIH)

0.005 ppm

STEL (ACGIH)

0.01 ppm

PEL (OSHA)

0.005 ppm

MAK

0.005 ppm

IDLH (NIOSH)

1 ppm

Excerpts from Documentation for IDLHs

Human data: None relevant for use in determining the revised IDLH.

Vapor Pressure

171 mm Hg

Odor Threshold Low

0.97 ppm

Lethal Concentration

LC50 (rat) = 6 ppm/4H

Explanatory Notes

Odor threshold from AIHA; Flash point = 86 deg F; Pyrophoric (Ignites upon contact with air;) [CHEMINFO]

Flammability (NFPA)

4: Burns readily

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: