Agent Name

Cyclohexanol

CAS Number

108-93-0

Formula

C6-H12-O

Major Category

Other Classes

Synonyms

1-Cyclohexanol; Adronal; Adronol; Anol; Cicloesanolo [Italian]; Cyclohexanol; Cyclohexanone cyclohexanol mixture; Cyclohexyl alcohol; Cykloheksanol [Polish]; Hexahydrophenol; Hexalin; Hydralin; Hydrophenol; Hydroxycyclohexane; Naxol; Phenol, hexahydro-; [ChemIDplus] UN1993

Category

Alcohols and Polyols, Other

Description

Sticky solid or colorless to light-yellow liquid (above 77 degrees F) with a camphor-like odor; [NIOSH]

Sources/Uses

Used in the production of nylon, paints, plastics, detergents, textiles, and pesticides; [ACGIH]

Comments

Liquid or solid form causes first degree burns on short exposure; [CHRIS] Skin absorption and narcosis seen in acute animal studies; [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; [ICSC] Causes liver and kidney injury in high-dose animal studies; [HSDB]

Exposure Assessment
BEI

Screen for 1,2-Cyclohexandiol (with hydrolysis) in urine at end of shift at end of workweek;Screen for Cyclohexanol (with hydrolysis) in urine at end of shift;

Skin Designation (ACGIH)

Yes

TLV (ACGIH)

50 ppm

PEL (OSHA)

50 ppm

IDLH (NIOSH)

400 ppm

Excerpts from Documentation for IDLHs

Human data: The estimated acceptable concentration for 8 hours was reported in volunteers to be less than 100 ppm [Nelson et al. 1943].

Vapor Pressure

0.8 mm Hg

Odor Threshold Low

0.05 ppm

Odor Threshold High

0.15 ppm

Lethal Concentration

LC (rat) > 6,500 mg/m3/1h (inhalation)

Explanatory Notes

Detection odor threshold from AIHA (mean = 0.16 ppm); Flash point = 63 deg C;

Half Life

No reports found; [TDR, p. 430]

Reference Link

ICSC: Cyclohexanol

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: