Agent Name

Veratridine

CAS Number

71-62-5

Formula

C36-H51-N-O11

Major Category

Biological Agents

Synonyms

3-Veratroylveracevine; 4,9-Epoxycevane-3,4,12,14,16,17,20-heptol 3-(3,4-dimethoxybenzoate); Cevane-3-beta,4-alpha,12,14,16-beta,17,20-heptol, 4,9-epoxy-, 3-(3,4-dimethoxybenzoate); Veratrine; Veratrine (amorphous); Veratrine (amorphous) (VAN); 4,9-Epoxycevane-3beta,4alpha,12,14,16beta,17,20-heptol 3-veratrate; Cevane-3,4,12,14,16,17,20-heptol, 4,9-epoxy-, 3-(3,4-dimethoxybenzoate), (3beta,4alpha,16beta)-; [ChemIDplus]

Category

Plant Toxins

Description

Yellowish-white solid; [Merck Index]

Sources/Uses

Isolated from seeds of Schoenocaulon officinale and the rhizome of Veratrum album; [Merck Index] A component of sabadilla (insecticide); [HSDB]

Comments

Emergency treatment: "Plants- veratrum alkaloids"; Excessive amounts can cause death by central respiratory depression; [HSDB] Veratrum alkaloids (e.g., black snakeroot, false hellebore, and skunk cabbage) cause gastroenteritis, bradycardia, paresthesias, AV block, and syncope;; [Olson, p. 376-92] A strong irritant; May be fatal by all routes of exposure; May cause corrosive injuries to mucous membranes and upper respiratory tract; May cause disturbances to nervous system; A powerful muscle stimulant; Possible reproductive toxin; [Aldrich MSDS]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

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