Agent Name

2-Nitrophenol

CAS Number

88-75-5

Formula

C6-H5-N-O3

Major Category

Nitrogen Compounds

Synonyms

2-Hydroxynitrobenzene; 2-Nitrophenol; Phenol, 2-nitro-; Phenol, o-nitro-; o-Hydroxynitrobenzene; o-Nitrofenol [Czech]; o-Nitrophenol; [ChemIDplus] UN1663

Category

Nitrophenols

Description

Light yellow solid with a peculiar aromatic smell;

Sources/Uses

Used to produce drugs, fungicides, and dyes; used to darken leather; [ATSDR ToxProfiles]

Comments

4-Nitrophenol is more toxic than 2-nitrophenol in animals. Rats exposed to 112 mg/m3 for 2 weeks develop methemoglobinemia. No effect after dust exposures of 30 mg/m3 for 3-6 hours/day, 5 days a week for 4 weeks; [ATSDR ToxProfiles] Can be absorbed through intact skin; [HSDB] A mild skin and eye irritant; Can induce methemoglobinemia after ingestion; [ICSC]

Exposure Assessment
Vapor Pressure

0.11 mm Hg

Reference Link

ATSDR - ToxFAQs - Nitrophenols

Adverse Effects
Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.