Agent Name

N-Nitrosodi-n-propylamine

Alternative Name

NDPA

CAS Number

621-64-7

Formula

C6-H14-N2-O

Major Category

Nitrogen Compounds

Synonyms

NDPA; 1-Propanamine, N-nitroso-N-propyl-; Di-n-propylnitrosamine; Di-n-propylnitrosoamine; Dipropylamine, N-nitroso-; Dipropylnitrosamine; N,N-Di-n-propylnitrosamine; N,N-Dipropylnitrosamine; N-Nitroso-N-propyl-1-propanamine; N-Nitrosodi-n-propylamine; N-Nitrosodipropylamine; Nitrosodipropylamine; Propanamine, N-nitroso-N-propyl-; Propylamine, N-nitroso-N-di-; [ChemIDplus] UN3077

Category

Nitrosamines

Description

Yellow liquid; [HSDB]

Sources/Uses

Not produced in the United States; used primarily for research; [HSDB] "Small amounts of N-nitrosodi-n-propylamine are produced as a side reaction during some manufacturing processes, as a contaminant in some commonly available weed killers (dinitroaniline-based), and during the manufacture of some rubber products. When exposed to sunlight, N-nitrosodi-n-propylamine usually does not last for more than a day." [ATSDR ToxProfiles]

Comments

In animal experiments, N-nitrosodi-n-propylamine causes hepatic injury after acute exposure and cancer of the liver after chronic exposure. [ATSDR ToxProfiles]

Exposure Assessment
Vapor Pressure

0.08 mm Hg

Explanatory Notes

Carcinogen--No TLV;

Reference Link

ATSDR - ToxFAQs - n-Nitrosodi-n-propylamine

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Possible Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.