Agent Name

1,1,1,3,3,3-Hexafluoro-2-propanol

CAS Number

920-66-1

Formula

C3-H2-F6-O

Major Category

Other Classes

Synonyms

1,1,1,3,3,3-Hexafluoroisopropanol; 1,1,1,3,3,3-Hexafluoroisopropyl alcohol; 2,2,2-Trifluoro-1-(trifluoromethyl)ethanol; 2H-Hexafluoroisopropanol; Bis(trifluoromethyl)methanol; Ethanol, 2,2,2-trifluoro-1-(trifluoromethyl)-; HFIP; Hexafluoro-2-propanol; Hexafluoroisopropanol; Hexafluoroisopropyl alcohol; 1,1,1,3,3,3-Hexafluoropropan-2-ol; 2-Propanol, 1,1,1,3,3,3-hexafluoro-; [ChemIDplus]

Category

Alcohols and Polyols, Other

Description

Colorless to light colored liquid; [CAMEO] Melting point = -4 deg C; Miscible in water; [MSDSonline]

Comments

Destructive to tissues and can cause chemical pneumonitis, liver and kidney injury, convulsions, coma, and death; [CAMEO] Corrosive to skin; Harmful by inhalation; Can cause chemical pneumonitis; [MSDSonline]

Exposure Assessment
Vapor Pressure

159 mm Hg

Lethal Concentration

LC50 (rat) = 1,974 ppm/4h

Explanatory Notes

Flash point > 93 deg C; [CAMEO] ERG guide is for "Corrosive liquid, n.o.s."

Adverse Effects
Toxic Pneumonitis

Yes

Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: