Agent Name

Chlorothalonil

CAS Number

1897-45-6

Formula

C8-Cl4-N2

Major Category

Pesticides

Synonyms

Forturf; Bravo; Exotherm; m-TCPN; Sweep; TCIN; Termil; TPN; Daconil; 2,4,5,6-Tetrachloro-1,3-Benzenedicarbonitrile, 2,4,5,6-tetrachloro-; 1,3-Dicyanotetrachlorobenzene; 2,4,5,6-Tetrachloro-1,3-benzenedicarbonitrile (8CI)(9CI); 2,4,5,6-Tetrachloro-3-cyanobenzonitrile; 2,4,5,6-Tetrachloroisophthalonitrile; Bravo; Bravo 500; Bravo 6F; Bravo-W-75; Chloroalonil; Chlorthalonil [German]; Clorthalonil [German]; Clortocaf ramato; Clortosip; DAC 2787; Daconil; Daconil 2787; Daconil 2787 W-75 Fungicide; Daconil 2787 W75; Daconil 2787 flowable fungicide; Daconil Flowable; Daconil M; Dacosoil; Exotherm; Exotherm termil; Faber; Forturf; Isophthalonitrile, 2,4,5,6-tetrachloro-; Nopcocide; Nopcocide N-96; Nopcocide N40D & N96; Repulse; Sweep; TPN (pesticide); Termil; Terraclactyl; Tetrachlorisoftalonitril [Czech]; Tetrachloroisophthalonitrile; m-TCPN; m-Tetrachlorophthalonitrile; meta-TCPN; meta-Tetrachlorophthalodinitrile; Isophthalonitrile, tetrachloro-; [ChemIDplus] UN2588

Category

Fungicides

Description

Colorless or white odorless solid; [HSDB] White solid; Formulated in the form of dust, granular, wettable powder, dry flowable, flowable concentrate, impregnated material, and ready-to-use; [Reference #2]

Sources/Uses

Used as a fungicide on vegetables, trees, fruits, turf, ornamentals, and other crops; [EXTOXNET] Used as a fungicide and preservative in paints, adhesives, and wood; [Kanerva, p. 786] Used as a biocide in paint; [Adams, p. 475] Used as a preservative in adhesives; [HSDB] Act mainly as a fungicide and mildewicide, but possesses some bactericidal, microbicidal, algaecidal, insecticidal, and acaricidal properties; Used as broad spectrum non-systemic pesticide, mildewicide for paints and other surface treatments, and protectant for wood; Contains hexachlorobenzene (HCB) as an impurity; [Reference #2]

Comments

No cases of systemic poisoning have been documented, but allergic contact dermatitis has been reported. [EPA Pesticides] Occupational asthma reported in farmer; [Malo] It is a strong skin irritant; Allergic contact dermatitis reported in flower and vegetable growers and carpenters; [Kanerva, p. 786] Chlorothalonil can cause immunologic, occupational contact urticaria. [Kanerva, p. 219] A severe eye, mild skin, and respiratory tract irritant; May cause skin sensitization; [ICSC] Reports of contact dermatitis in agricultural workers, cabinet makers, and employees of a chlorothalonil manufacturing facility; Occupational asthma also reported; Workers in a packaging plant reported intense pain on ocular exposure; Moderate conjunctivitis and corneal irritation (no corneal opacity) were observed; [HSDB] A mild skin irritant; Can cause permanent eye injury; A weak skin sensitizer; [Syngenta MSDS]

Reference Link

Occupational asthma induced by the fungicide tetrachloroisophthalonitrile

Exposure Assessment
Vapor Pressure

5.7E-7 mm Hg

Lethal Concentration

LC50 (rat) = 92 mg/m3

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Pesticide, solid, toxic, n.o.s."

Reference Link

EPA Pesticide Chemical Search

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

IARC Carcinogen

Possible Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: