Agent Name

Methyltetrahydrophthalic anhydride

CAS Number

26590-20-5

Formula

C9-H10-O3

Major Category

Plastics & Rubber

Synonyms

1,3-Isobenzofurandione, 3a,4,7,7a-tetrahydromethyl-; AC 220; AC 220J; Lindride; Methyl tetrahydrophthalic anhydride; 1,2,3,6-Tetrahydromethylphthalic anhydride; Phthalic anhydride, methyltetrahydro-; [ChemIDplus]

Category

Acid Anhydrides, Cyclic

Description

Liquid; [ICSC]

Sources/Uses

Exposures have been reported in workers applying polyester resin glues and curing epoxy and alkyl resins; [NIOSHTIC] Used as a hardener in epoxy resin systems; [ChemIDplus]

Comments

Occupational asthma reported in workers curing epoxy resins; [Malo] [Tarvainen K, et al. Immunologic contact urticaria due to airborne methylhexahydrophthalic and methyltetrahydrophthalic anhydrides. Contact Dermatitis. 1995 Apr;32(4):204-9.] Prolonged or repeated exposure may cause asthma and contact urticaria; [ICSC] An irritant; [MP Biomedicals MSDS] See "ACID ANHYDRIDES."

Reference Link

Allergy to methyltetrahydrophthalic anhydride in epoxy resin workers

Exposure Assessment
Explanatory Notes

See "2018 Notice of Intended Changes." [TLVs and BEIs]

Reference Link

Exposure assessment and sensitisation in workers exposed to organic acid anhydrides

Adverse Effects
Asthma

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: