Agent Name

Isophorone diamine

CAS Number

2855-13-2

Formula

C10-H22-N2

Major Category

Nitrogen Compounds

Synonyms

3-Aminomethyl-3,5,5-trimethylcyclohexylamine; 5-Amino-1,3,3-trimethylcyclohexanemethylamine; Cyclohexanemethanamine, 5-amino-1,3,3-trimethyl-; Cyclohexanemethylamine, 5-amino-1,3,3-trimethyl-; 3-Aminomethyl-3,5,5-trimethylcyclohexylamine; Cyclohexanemethanamine, 5-amino-1,3,3-trimethyl-; Isophoronediamine; [ChemIDplus] 1,3,3-Trimethyl-1-aminomethyl-5-aminocyclohexane; 1-Amino-3,3,5-trimethyl-5-aminomethylcyclohexane; 1-Amino-3-(aminomethyl)-3,5,5-trimethylcyclohexane; 3,3,5-Trimethyl-5-aminomethylcyclohexylamine; 3-Aminomethyl-3,5,5-trimethylcyclohexylamine; 5-Amino-1,3,3-trimethylcyclohexanemethanamine; Araldite HY 5083; Chemammina CA 17; IPD; Isoforondiamina (Spanish DOT); Isophoronediamine (French DOT); Luxam IPD; Vestamin IPD; [CAMEO] 1-Amino-3-aminomethyl-3,5,5-trimethylcyclohexane; 3-Aminomethyl-3,5,5-trimethylcyclohexylamin (German); Degamin IPDA; Isophorondiamin (German); [Reference #2] UN2289

Category

Amines, Cyclic

Description

Colourless liquid; mp = 10 deg C; [ICSC] Clear light yellow liquid; [Aldrich MSDS]

Sources/Uses

Used to make its corresponding diisocyanate, polymers (mainly polyurethanes), and to cure epoxy resins; [HSDB] Used to make hardeners for epoxy resins and coatings (and directly as a hardener), in epoxy-based self-leveling and trowelable flooring systems, for paving, concrete protection, and repair, in coatings for corrosion protection of metal, adhesives, and anchoring compounds, and in paints; Also used to make dyes and non-crystalline specialty polyamides; [Reference #2]

Comments

If inhaled, it can provoke coughing and nausea. [CHRIS] An epoxy resin hardener and suspected cause of occupational asthma, isophorone diamine is one component of mixtures causing occupational asthma in two separate documented cases: (1) [Occupational asthma due to EPO 60. Lambourn EM, Hayes JP, McAllister WA, Taylor AJ. Br J Ind Med 1992 Apr;49(4):294-5]; and (2) [Occupational asthma caused by a hardener containing an aliphatic and a cycloaliphatic diamine. Aleva RM et al. Am Rev Respir Dis 1992 May;145(5):1217-8] Corrosive to skin, eyes, and respiratory tract; Inhalation can cause pulmonary edema; May cause skin sensitization. [ICSC] Danger of skin sensitization; [MAK] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Harmful by ingestion; [Aldrich MSDS]

Reference Link

Occupational asthma caused by a hardener containing an aliphatic and a cycloaliphatic diamine

Exposure Assessment
Vapor Pressure

0.01 mm Hg

Explanatory Notes

Flash point =112 deg C;

Reference Link

OECD SIDS: 3-Aminomethyl-3,5,5-trimethylcyclohexylamine - 2004

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: