Agent Name

N,N-Dimethyl-1,3-propanediamine

Alternative Name

DMAPA

CAS Number

109-55-7

Formula

C5-H14-N2

Major Category

Nitrogen Compounds

Synonyms

DMAPA; 1,3-Propanediamine, N,N-dimethyl-; 1-(Dimethylamino)-3-aminopropane; 1-Amino-3-dimethylaminopropane; 3-(Dimethylamino)-1-propanamine; 3-(Dimethylamino)-1-propylamine; 3-(Dimethylamino)propylamine; 3-Amino-1-(dimethylamino)propane; N,N-Dimethyl-1,3-diaminopropane; N,N-Dimethyl-1,3-propanediamine; N,N-Dimethyl-1,3-propylenediamine; N,N-Dimethyl-N-(3-aminopropyl)amine; N,N-Dimethylpropylenediamine; N,N-Dimethyltrimethylenediamine; N-Dimethyltrimethylenediamine; Propylamine, 3-(N,N-dimethylamino)-; gamma-(Dimethylamino)propylamine; [ChemIDplus] UN1993; UN2734

Category

Amines, Aliphatic

Description

Colorless liquid; [HSDB]

Sources/Uses

Used as curing agent for epoxy resins and polyurethanes; used as chemical intermediate in the production of surface active agents for water treatment, motor oil additives, fabric softeners, etc. [HSDB]

Comments

Occupational asthma reported in workers manufacturing skis; [Malo] Allergic contact dermatitis has been reported in workers handling epoxy resins or using products containing cocamidopropyl betaine. DMAPA is a contaminant in such products and the responsible allergen. [Kanerva, p. 1785] A corrosive substance that can cause pulmonary edema; A skin sensitizer; [ICSC] A lachrymator; [CHEMINFO]

Reference Link

Respiratory effects of occupational exposure to an epoxy resin system

Exposure Assessment
Vapor Pressure

9.75 mm Hg

Odor Threshold Low

0.1 ppm

Explanatory Notes

Vapor pressure at 30 degrees C = 1.33 kPa (9.75 mm Hg); [ICSC] Flash point = 90 deg F; Odor threshold from CHEMINFO;

Reference Link

3-Dimethylaminopropylamine: a key substance in contact allergy to cocamidopropylbetaine?

Adverse Effects
Skin Sensitizer

Yes

Lacrimator

Yes

Asthma

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: