Agent Name

4-Methylmorpholine

CAS Number

109-02-4

Formula

C5-H11-N-O

Major Category

Nitrogen Compounds

Synonyms

1-Methylmorpholine; 4-Methylmorfolin [Czech]; 4-Methylmorpholine; Morpholine, N-methyl-; N-Methylmorpholine; [ChemIDplus] UN2535

Category

Morpholines

Description

A water-white liquid with an ammonia-like odor; [CAMEO]

Sources/Uses

"Used as a solvent and to make pharmaceuticals." [CAMEO] Used in poyurethane foam production; [Reference #1]

Comments

Reported cause of occupational asthma in 16.6% of 48 chemical manufacturing workers; [Malo] Corrosive to skin and eyes; [CAMEO]

Reference Link

Amines: possible causative agents in the development of bronchial hyperreactivity in workers manufacturing polyurethanes from isocyanates

Exposure Assessment
Vapor Pressure

13.2 mm Hg

Lethal Concentration

LCLo (rat) = 2,000 ppm/4h

Explanatory Notes

Flash point = 75 deg F;

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Asthma

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: