Agent Name

Copper(II) arsenite

Alternative Name

Cupric arsenite

CAS Number

10290-12-7

Formula

As-H-O3.Cu

Major Category

Metals

Synonyms

Acid copper arsenite; Air-flo Green; Arsenious acid, copper(II) salt (1:1); Arsenious acid (H3AsO3), copper(2+) salt (1:1); Arsonic acid, copper(2+) salt (1:1); Copper arsenite; Copper orthoarsenite; Cupric Green; Cupric arsenite; Scheele's mineral; Scheeles Green; Swedish Green; [ChemIDplus] UN1586

Category

Arsenic Compounds, Inorganic

Description

Yellowish-green solid; Variable composition; [Merck Index]

Sources/Uses

Used as a pigment, wood preservative, insecticide, fungicide, and rodenticide; Some uses are diminished in recent years because dimethyl arsine may be liberated by action of molds; [HSDB]

Comments

Toxic by ingestion: Can cause severe gastroenteritis, loss of fluids and electrolytes, cardiac disorders, shock, and death; Other effects of arsenic poisoning are neuropathy, skin pigmentation, and injury to the liver, kidneys, and bone marrow; [ICSC] Acute copper poisoning after ingestion can cause liver injury, methemoglobinemia, and hemolytic anemia. Acute renal failure may result, secondary to massive hemoglobinuria. [Goldfrank, p. 1259] See "Copper." See "Arsenic" and the linked occupational diseases.

Restricted

Not found in any pesticide products registered in the US; [NPIRS]

Exposure Assessment
BEI

Inorganic arsenic plus methylated metabolites in urine = 35 ug As/L; end of workweek;

Bioaccumulates

Yes

TLV (ACGIH)

0.01 mg/m3, as As

PEL (OSHA)

0.01 mg/m3, as As

MAK

0.01 mg/m3, respirable fraction (Cu, inorganic cmpnds.)

IDLH (NIOSH)

5 mg/m3, as As

Adverse Effects
Anemia

Anemia, Hemolytic

Neurotoxin

Sensorimotor Neuropathy

Hepatotoxin

Hepatotoxin, Secondary

Reproductive Toxin

Yes

Methemoglobinemia

Methemoglobinemia, Secondary

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

ACGIH Carcinogen

Confirmed Human

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: