Agent Name

Lasamide

CAS Number

2736-23-4

Formula

C7-H5-Cl2-N-O4-S

Major Category

Other Classes

Synonyms

2,4-Dichloro-5-sulfamoylbenzoic acid; 2,4-Dichloro-5-sulphamoylbenzoic acid; 3-Sulfamoyl-4,6-dichlorobenzoic acid; 5-Aminosulfonyl-2,4-dichlorobenzoic acid; 5-Carboxy-2,4-dichlorobenzenesulfonamide; Benzoic acid, 2,4-dichloro-5-sulfamoyl-; Benzoic acid, 5-(aminosulfonyl)-2,4-dichloro-; [ChemIDplus]

Category

Benzenesulfonic Acid Derivatives

Description

Powder; [MSDSonline]

Sources/Uses

Used to make furosemide (Lasix), a medication used as a diuretic; [Reference #1]

Comments

Exposure occurs during the handling, drying and packaging of lasamide at production plants in the Czech Republic, China, and India; Nonspecific bronchoconstriction tests were positive in 3 workers with occupational rhinitis and asthma; [Reference #1] A skin, eye, and respiratory tract irritant; [MSDSonline]

Reference Link

Occupational asthma and rhinitis in workers from a...[Scand J Work Environ Health. 2007] - PubMed Result

Adverse Effects
Asthma

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: