Agent Name

n-Butyl ether

CAS Number

142-96-1

Formula

C8-H18-O

Major Category

Solvents

Synonyms

1,1'-Oxybis(butane); 1-Butoxybutane; Butane, 1,1'-oxybis-; Butyl ether; Butyl oxide; Di-n-butyl ether; Dibutyl ether; Dibutyl oxide; Ether butylique [French]; n-Dibutyl ether; [ChemIDplus] UN1149

Category

Ethers (<C12)

Description

Colorless liquid with a mild ethereal odor; [Hawley]

Sources/Uses

Used as solvent (hydrocarbons, resins, fats, oils, organic acids, alkaloids, esters, and gums), extracting agent , intermediate, reaction medium, and in plutonium separation processes; [HSDB]

Comments

May form explosive peroxides; [Hawley] A skin, eye, and respiratory tract irritant; May have effects on CNS and liver; Defats the skin; [ICSC] A skin and eye irritant; [eChemPortal: ERMA] An irritant; Effects in high-dose animal studies include general anesthesia and fatty liver degeneration; [MSDSonline]

Exposure Assessment
Vapor Pressure

6.01 mm Hg

Lethal Concentration

LCLo (rat) = 4,000 ppm/4h

Explanatory Notes

Odor threshold high = 0.37 mg/m3, low = 2.50 mg/m3; [HSDB] The Guide in the Emergency Response Guidebook is for "Dibutyl ethers."

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: