Agent Name

4-Aminophenol

Alternative Name

p-Aminophenol

CAS Number

123-30-8

Formula

C6-H7-N-O

Major Category

Nitrogen Compounds

Synonyms

p-Aminophenol; 1-Amino-4-hydroxybenzene; 4-Amino-1-hydroxybenzene; 4-Aminophenol; 4-Hydroxyaniline; Activol; Azol; BASF Ursol P Base; Benzofur P; C.I. 76550; C.I. Oxidation Base 6; CI 76550; Certinal; Citol; Durafur Brown RB; Fouramine P; Fourrine 84; Fourrine P Base; Furro P Base; Nako Brown R; PAP; Paranol; Pelagol Grey P Base; Pelagol P Base; Renal AC; Rodinal; Tertral P base; Unal; Ursol P; Ursol P base; Zoba Brown P Base; p-Aminofenol [Czech]; p-Aminophenol; p-Hydroxyaniline; p-Hydroxyphenylamine; [ChemIDplus] UN2512

Category

Amino Phenols

Description

White or reddish-yellow crystals or light-brown powder that turns violet when exposed to light; [CAMEO]

Sources/Uses

Used as a dye for textiles, hair, furs, and feathers; also used as a photographic developer and chemical intermediate for pharmaceuticals and dyes; [HSDB]

Comments

The lethal oral dose in humans is in the range of 50-500 mg/kg. p-Aminiophenol induces methemoglobinemia in experimental animals, but it is not as potent as aniline. It is a potential sensitizer of the skin and respiratory tract. [HSDB] "Symptoms of exposure to this chemical may include asthma, irritation of the skin and eyes, dermatitis and methemoglobinemia with cyanosis; This compound is a skin and eye irritant and an allergen." [CAMEO] Danger of skin sensitization; [MAK]

Reference Link

Occupational allergic contact dermatitis in beauticians

Exposure Assessment
Vapor Pressure

4.0E-5 mm Hg

Lethal Concentration

LC50 (rat) =>5 mg/m3/1H

Explanatory Notes

Melting point = 367-369 degrees F; [CAMEO]

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: