Agent Name

Chloral hydrate

CAS Number

302-17-0

Formula

C2-H3-Cl3-O2

Major Category

Other Classes

Synonyms

1,1,1-Trichloro-2,2-dihydroxyethane; 1,1,1-Trichloro-2,2-ethanediol; 2,2,2-Trichloro-1,1-ethanediol; Aquachloral; Bi 3411; Chloradorm; Chloral monohydrate; Chloraldural [Swiss]; Chloraldurat [German]; Chloralex; Chlorali Hydras; Chloralvan; Cohidrate; Dormal; Escre; Felsules; Hydrate de chloral; Hynos; Kessodrate; Kloralhydrat; Knockout drops; Lorinal; Noctec; Novochlorhydrate; Nycoton; Nycton; Oradrate; Phaldrone; Rectules; SK-Chloral Hydrate; Somni SED; Somnos; Sontec; Tosyl; Trawotox; Trichloracetaldehyd-hydrat [German]; Trichloroacetaldehyde hydrate; Trichloroacetaldehyde monohydrate; Trichloroacetaldehyde, hydrated; [ChemIDplus]

Category

Halogenated Alcohols

Description

Colorless transparent solid with a penetrating, slightly acrid odor; [Hawley] Colorless or white solid; Colorless liquid; [HSDB] Crystalline solid; [MSDSonline]

Sources/Uses

Used as a drug (sedative and hypnotic), a rubefacient and liniment, a glue peptizing agent, and a chemical intermediate; [HSDB] Formed as by-product of drinking water chlorination; [IPCS]

Comments

A skin, eye, and respiratory tract irritant; A CNS depressant; [ICSC] A skin and mucous membrane irritant; May cause eye injury; [HSDB] A skin and eye irritant; [eChemPortal: ERMA; ESIS] An irritant; [MSDSonline] Liver injury reported after lethal doses, but not after therapeutic doses; [INCHEM: CICADS]

Exposure Assessment
Vapor Pressure

15 mm Hg

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Probable Carcinogen

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: