Agent Name

Pyrogallol

CAS Number

87-66-1

Formula

C6-H6-O3

Major Category

Other Classes

Synonyms

1,2,3-Benzenetriol; 1,2,3-Trihydroxybenzen [Czech]; 1,2,3-Trihydroxybenzene; 215; Benzene, 1,2,3-trihydroxy-; C.I. 76515; C.I. Oxidation Base 32; CI 76515; CI Oxidation Base 32; Fouramine Brown AP; Fourrine 85; Fourrine PG; PYROGALLOL; Pyro; Pyrogallic acid; [ChemIDplus]

Category

Phenols

Description

Odorless, white to gray solid; [CAMEO]

Sources/Uses

Used in photography and leather crafts; used in wool, fur, and hair dyeing; also used as an analytical chemistry reagent, an antioxidant for oils, and as a topical medication; [HSDB] Used in hair dyes and was used in photographic developers; [Kanerva, p. 1832] No longer used in hair dyes because of the frequency of allergic reactions; [Kanerva, p. 1516]

Comments

Reported human toxicity after ingestion includes methemoglobinemia, hemolysis of red blood cells, and damage to the liver and kidneys; [HSDB] An eye, respiratory tract, and mild skin irritant; May cause skin sensitization; [ICSC] Allergic contact dermatitis reported in hairdressers; [Kanerva, p. 1832] Toxic by ingestion with adverse effects including convulsions; [CAMEO]

Reference Link

Allergic reactions to a hairdressers' series: results from 9 European centres. The European Environmental and Contact Dermatitis Research Group (EECDRG)

Exposure Assessment
Vapor Pressure

0.000479 mm Hg

Reference Link

ICSC: Pyrogallic acid

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: