Agent Name

Glyceryl monothioglycolate

CAS Number

30618-84-9

Formula

C5-H10-O4-S

Major Category

Other Classes

Synonyms

Acetic acid, mercapto-, monoester with 1,2,3-propanetriol; Glycerol monomercaptoacetate; Glyceryl thioglycolate; Mercaptoacetic acid, monoester with 1,2,3-propanetriol; Acetic acid, 2-mercapto-, monoester with 1,2,3-propanetriol; Mercaptoacetic acid, monoester with propane-1,2,3-triol; Acetic acid, mercapto-, monoester with glycerol; [ChemIDplus] Sure Success Perm Part A; [Lanza Research MSDS]

Category

Thioglycolates

Description

Colorless viscous liquid with a mild sulfurous odor; [Lanza Research MSDS]

Sources/Uses

Allergic contact dermatitis in hairdressers; [Marks] Used in permanent hair waving; [REPROTOX]

Comments

Glyceryl thioglycolate (monothioglycolate) is the allergen in acid permanents. The allergen remains active in hair shafts for months and can be a source of chronic allergic contact dermatitis. [Marks, p. 178-9] Causes allergic dermatitis on topical exposure to human skin; [RTECS] Danger of skin sensitization; [MAK] Inhalation can irritate respiratory tract; May cause dermatitis in certain individuals; [Lanza Research MSDS]

Reference Link

Allergic reactions to a hairdressers' series: results from 9 European centres. The European Environmental and Contact Dermatitis Research Group (EECDRG).

Adverse Effects
Skin Sensitizer

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: