Agent Name

Bisphenol A

Alternative Name

4,4'-Isopropylidenediphenol

CAS Number

80-05-7

Formula

C15-H16-O2

Major Category

Plastics & Rubber

Synonyms

4,4'-Isopropylidenediphenol; 2,2-(4,4'-Dihydroxydiphenyl)propane; 2,2-Bis(4-hydroxyphenyl)propane; 2,2-Bis(hydroxyphenyl)propane; 2,2-Bis(p-hydroxyphenyl)propane; 2,2-Bis-4'-hydroxyfenylpropan [Czech]; 2,2-Di(4-hydroxyphenyl)propane; 2,2-Di(4-phenylol)propane; 4,4'-(1-Methylethylidene)bisphenol; 4,4'-Bisphenol A; 4,4'-Dihydroxydiphenyl-2,2-propane; 4,4'-Dihydroxydiphenyldimethylmethane; 4,4'-Dihydroxydiphenylpropane; 4,4'-Isopropylidene diphenol; 4,4'-Isopropylidenebisphenol; 4,4'-Isopropylidenediphenol; Biphenol A; Bis(4-hydroxyphenyl) dimethylmethane; Bis(4-hydroxyphenyl)dimethylmethane; Bis(4-hydroxyphenyl)propane; Bisferol A [Czech]; Bisphenol; Bisphenol A; Bisphenol-A; DIAN; Diano; Dimethyl bis(p-hydroxyphenyl)methane; Dimethylbis(p-hydroxyphenyl)methane; Dimethylmethylene-p,p'-diphenol; Diphenylolpropane; Ipognox 88; Isopropylidenebis(4-hydroxybenzene); Parabis A; Phenol, (1-methylethylidene)bis-; Phenol, 4,4'-(1-methylethylidene)bis-; Phenol, 4,4'-dimethylmethylenedi-; Phenol, 4,4'-isopropylidenedi-; Pluracol 245; Propane, 2,2-bis(p-hydroxyphenyl)-; Rikabanol; Ucar bisphenol A; Ucar bisphenol HP; beta,beta'-Bis(p-hydroxyphenyl)propane; beta-Di-p-hydroxyphenylpropane; p,p'-Bisphenol A; p,p'-Dihydroxydiphenyldimethylmethane; p,p'-Dihydroxydiphenylpropane; p,p'-Isopropylidenebisphenol; p,p'-Isopropylidenediphenol; [ChemIDplus]

Category

Epoxy Resins

Description

White crystalline solid or flakes with a mild phenolic odour; [CHEMINFO]

Sources/Uses

Used as a chemical intermediate, mainly for epoxy resins and polycarbonate resins; [HSDB] Used with epichlorohydrin to produce epoxy resins; [Kanerva, p. 1759]

Comments

A skin, eye, and respiratory tract irritant; "Repeated or prolonged contact may cause skin sensitization." [ICSC] Reports of sensitization are rare; A possible sensitizer in vinyl gloves; [Kanerva, p. 1759] Danger of photo-contact sensitization; [MAK]

Reference Link

Occupational allergic contact dermatitis caused by epoxy diacrylate in ultraviolet-light-cured paint, and bisphenol A in dental composite resin

Exposure Assessment
MAK

5 mg/m3, inhalable fraction

Vapor Pressure

3.91E-7 mm Hg

Lethal Concentration

LC (mice) > 1,700 mg/m3/2h; (inhalation)

Explanatory Notes

Flash point = 175 deg F;

Reference Link

ICSC: Bisphenol A

Adverse Effects
Skin Sensitizer

Yes

Dermatotoxin

Contact Dermatitis, Photoallergic

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: