Agent Name

gamma-Glycidoxypropyltrimethoxysilane

CAS Number

2530-83-8

Formula

C9-H20-O5-Si

Major Category

Plastics & Rubber

Synonyms

((3-(Trimethoxysilyl)propoxy)methyl)oxirane; (3-(Glycidyloxy)propyl)trimethoxysilane; (3-Glycidoxypropyl)trimethoxysilane; 1-(Glycidyloxy)-3-(trimethoxysilyl)propane; 3-(2,3-Epoxypropoxy)propyltrimethoxysilane; 3-(Trimethoxysilyl)propyl glycidyl ether; A 187; DZ 6040; Glycidyl 3-(trimethoxysilyl)propyl ether; Glycidyloxypropyltrimethoxysilane; KBM 403; KBM 430; NUCA 187; Silan A 187; Silane A 187; Silane Z 6040; Silane-y-4087; Silicone A-187; Silicone KBM 403; Union carbide A-187; Y 4087; Z 6040; Oxirane, 2-((3-(trimethoxysilyl)propoxy)methyl)-; Silane, 3-(2,3-epoxypropoxy)propyltrimethoxy-; [ChemIDplus] Trimethoxy(3-(oxyrynylmethoxy)propyl)-silane; TMSPGE; [eChemPortal: SIDSUNEP]

Category

Glycidyl Ethers

Description

Liquid; [eChemPortal: SIDSUNEP] Clear colorless liquid; [MSDSonline]

Sources/Uses

Used as additive (cross-linking agent) for adhesion promotion in adhesives, sealants, coatings, and composites; Used in reinforcing glass fibers and foundry resins; [eChemPortal: SIDSUNEP]

Comments

Mildly irritating to skin and eyes; Not a known skin sensitizer; Rapidly hydrolyzes into methanol and silanetriols; Oral LD50 (rats) = 7010 to 16900 mg/kg and dermal LD50 (rats) = 6800 mg/kg; [Reference #1] May cause irritation; May form siloxane polymer on contact with skin, eyes, or lungs; [MSDSonline]

Reference Link

OECD SIDS: Trimethoxy[3-(oxiranylmethoxy)propyl]-silane - 2004

Exposure Assessment
Vapor Pressure

0.002 mm Hg

Lethal Concentration

LCLo (rat) =5,300 mg/m3/4h

Reference Link

Contact allergy to allyl glycidyl ether present as an impurity in 3-glycidyloxypropyltrimethoxysilane, a fixing additive in silicone and polyurethane resins.

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: