Agent Name

2-Bromo-4-hydroxyacetophenone

CAS Number

2491-38-5

Formula

C8-H7-Br-O2

Major Category

Other Uses

Synonyms

1-(4-Hydroxyphenyl)-2-bromoethanone; 2-Bromo-4'-hydroxyacetophenone; Busan 90; 2-Bromo-1-(4-hydroxyphenyl)ethan-1-one; Acetophenone, 2-bromo-4'-hydroxy-; Ethanone, 2-bromo-1-(4-hydroxyphenyl)-; [ChemIDplus] BHAP; Busan 93; Busan 1130; [Reference #1]

Category

Biocides/Disinfectants

Description

Reddish-brown odorless liquid; [Reference #1]

Sources/Uses

Used as microbiocide/microbiostat for control of slime forming bacteria and fungi in water cooling systems, oil recovery drilling muds and secondary injection water, pulp and paper water systems, adhesives, coatings, latex paints, and wet-end additives, and industrial processing chemicals; [Reference #1]

Comments

Erythema and edema progressing to subcutaneous hemorrhage, eschar, scabbing, necrosis, and exfoliation were observed in 21 day dermal study of rabbits (no systemic toxicity observed); No evidence of developmental toxicity; [Reference #1] After a spill of this slimicide at a papermill, workers developed recurrent allergic contact dermatitis. [Kanerva, p. 1761]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
Vapor Pressure

1.1E-5 mm Hg

Lethal Concentration

LC50 (rat) = 190 mg/m3/4hr

Reference Link

Allergic contact dermatitis from a paper mill slimicide containing 2-bromo-4'-hydroxyacetophenone.

Adverse Effects
Skin Sensitizer

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: