Agent Name

Mefluidide

CAS Number

53780-34-0

Formula

C11-H13-F3-N2-O3-S

Major Category

Pesticides

Synonyms

5'-(1,1,1-Trifluoromethanesulfonamido)acet-2',4'-xylidide; 5'-(1,1,1-Trifluoromethanesulphonamido)acet-2',4'-xylidide; 5-Acetamido-2,4-dimethyltrifluoromethanesulfonanilide; Acetamide, N-(2,4-dimethyl-5-(((trifluoromethyl)sulfonyl)amino)phenyl)-; Embark; Embark 2S; Embark plant growth regulator; MBR 12325; Mefluidide; N-(2,4-Dimethyl-5-(((trifluoromethyl)sulfonyl)amino)phenyl)acetamide; Trim-Cut; VEL 3973; Vistar; Vistar herbicide; 2',4'-Dimethyl-5'-(trifluoromethanesulphonamido)acetanilide; Acetanilide, 2',4'-dimethyl-5'-((trifluoromethyl)sulfonamido)-; [ChemIDplus]

Category

Plant Growth Regulators

Description

Solid; [Merck Index] Formulations include granular, ready-to-use liquid, and soluble liquid concentrate; [Reference #1] White, odorless, crystalline solid; [Chem Service MSDS]

Sources/Uses

Used as a plant growth regulator and herbicide; [Merck Index] Used as an anilide post-emergence plant growth regulator to suppress seed heads and fruiting and to slow plant growth to reduce maintenance; Registered for non-crop land (i.e. industrial, roadside, and public areas) and residential turf; Multiple products also contain additional plant growth regulators or herbicides (i.e. Paclobutrazol and Imazapyr); [Reference #1] Used to accelerate sugar cane ripening; [HSDB]

Comments

Mefluidide diethanolamine salt (Mefluidide-diolamine CAS# 53780-36-2) and mefluidide potassium salt (Mefluidide-potassium CAS# 83601-83-6) are considered toxicologically equivalent; Causes kidney injury and weight loss in chronic studies of dogs; Rats and rabbits exhibit tremors, hunched posture, salivation, and weight loss; Increased fetal losses in rats at doses maternally toxic; [Reference #1] A dose of 60 ppm was necessary for detection in milk of dairy cows fed for one month (no adverse effects to milk yield or quality); [REPROTOX] Hepatotoxicity observed in 18-month feeding study of rats; Decreased weaning weights noted in 3-generation study of rats (days 14-21 of lactation); No evidence of teratogenicity; [HSDB] An eye irritant; [Chem Service MSDS]

Restricted

No registered food/feed uses and no food tolerances in the US; [Reference #1]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
Lethal Concentration

LC50 (rat) > 5,400 mg/m3

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Processes

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