Agent Name

Metaldehyde

CAS Number

108-62-3

Formula

C8-H16-O4

Major Category

Pesticides

Synonyms

2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane; Acetaldehyde, tetramer; Ariotox; Cekumeta; Corry's Slug Death; Halizan; Metacetaldehyde; Metaldehyd [German]; Metaldeide [Italian]; Metason; Slug-Tox; r-2,c-4,c-6,c-8-Tetramethyl-1,3,5,7-tetroxocane; 1,3,5,7-Tetroxocane, 2,4,6,8-tetramethyl-; 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane; [ChemIDplus] UN1332

Category

Molluscicides

Description

Solid; [IUCLID] Formulated as granules, pellets, mini-pellets, meal, paste, and liquid; [Reference #1] Colorless or white solid; [Reference #2] White odorless powder; [Alfa Aesar MSDS]

Sources/Uses

Used for control of snails in seed crops, turf, ornamentals, berries, citrus, vegetables, and other crops; [Reference #1] Used for synthesis in the chemical industry, as odor agent, and as pesticide; [IUCLID] Used as molluscicide, solid fuel for small heaters (alcohol replacement), and fire starter; [Reference #2]

Comments

Not irritating to skin and slightly irritating to eyes of rabbits; Neurological effects (ataxia, twitching, tremors, and hind-limb paralysis) observed in studies of dogs and rats; No increased susceptibility of fetuses seen in developmental toxicity and 2-generation reproduction studies of rats and rabbits; Atrophy of the testes and prostate observed in chronic oral study of dogs (LOAEL = 90 mg/kg/day); [Reference #1] Slowly hydrolyzed in acidic media (i.e., in the stomach) to acetaldehyde (the main toxicologically significant component) which is further oxidized to acetic acid; A skin, eye, and mucous membrane irritant; May be corrosive to eyes; Inhalation of fumes can cause CNS depression, convulsions, and coma; Interferes with reproductive process in rats; No evidence of teratogenicity, carcinogenicity, or mutagenicity; [Reference #2] Highly flammable; An irritant; Toxic by ingestion; [Alfa Aesar MSDS] See "Polyacetaldehyde."

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
Lethal Concentration

LC50 (rat) = 3,140 mg/m3/4hr

Reference Link

INCHEM PIM: Metaldehyde - Updated/Peer reviewed 1999

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: