Agent Name

Butyraldehyde

CAS Number

123-72-8

Formula

C4-H8-O

Major Category

Other Classes

Synonyms

1-Butanal; Aldehyde butyrique [French]; Aldeide butirrica [Italian]; Butal; Butaldehyde; Butalyde; Butanal; Butanaldehyde; Butylaldehyde; Butyral; Butyraldehyd [German]; Butyric aldehyde; n-Butyraldehyde; [ChemIDplus] UN1129

Category

Aldehydes

Description

A clear liquid with a pungent odor; [AIHA] Colorless liquid; [ICSC] Unpleasant rancid/sweet odor; [OECD SIDS]

Sources/Uses

Used to make rubber accelerators, solvents, synthetic resins, high polymers, plasticizers, and other chemicals; [HSDB] Used as a flavoring agent and "generally recognized as safe" by the FDA; [AIHA] Nearly all manufacturing, processing, and use confined to enclosed processes, with more than 90% being used as on-site reactant (making butanol, butyric acid, and 2-ethylhexanol); [OECD SIDS]

Comments

If left on clothing, can cause reddening of skin; [CHRIS] Butyraldehyde is a skin irritant. [Quick CPC] May form explosive peroxides; May polymerize; A skin, eye, and respiratory tract irritant; [ICSC] May cause burns to skin and eyes; Inhalation may cause spasm, edema of the larynx and bronchi, chemical pneumonitis, and pulmonary edema; [HSDB] A severe irritant in animal experiments; In subchronic inhalation studies, 50 ppm was the no-observable-effect level and 117 ppm produced eye and upper respiratory tract irritation; Caused anesthetic effects in lethal concentration studies; [OECD SIDS] See "ALDEHYDES."

Exposure Assessment
WEEL

25 ppm

Vapor Pressure

111 mm Hg

Odor Threshold Low

0.005 ppm

Odor Threshold High

9 ppm

Lethal Concentration

LC50 (rat) = 47,560 mg/m3/4hr

Explanatory Notes

Flash point = 20 deg F; Odor thresholds from AIHA; Odor recognition threshold = 0.039 ppm; [OECD SIDS]

Adverse Effects
Toxic Pneumonitis

Yes

Neurotoxin

Other CNS Neurotoxin

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: