Agent Name

Butyraldehyde

CAS Number

123-72-8

Formula

C4-H8-O

Major Category

Other Classes

Synonyms

1-Butanal; Aldehyde butyrique [French]; Aldeide butirrica [Italian]; Butal; Butaldehyde; Butalyde; Butanal; Butanaldehyde; Butylaldehyde; Butyral; Butyraldehyd [German]; Butyric aldehyde; n-Butyraldehyde; [ChemIDplus] UN1129

Category

Aldehydes

Description

A clear liquid with a pungent odor; [AIHA] Colorless liquid; [ICSC] Unpleasant rancid/sweet odor; [OECD SIDS]

Sources/Uses

Used to make rubber accelerators, solvents, synthetic resins, high polymers, plasticizers, and other chemicals; [HSDB] Used as a flavoring agent and "generally recognized as safe" by the FDA; [AIHA] Nearly all manufacturing, processing, and use confined to enclosed processes, with more than 90% being used as on-site reactant (making butanol, butyric acid, and 2-ethylhexanol); [OECD SIDS]

Comments

If left on clothing, can cause reddening of skin; [CHRIS] Butyraldehyde is a skin irritant. [Quick CPC] May form explosive peroxides; May polymerize; A skin, eye, and respiratory tract irritant; [ICSC] May cause burns to skin and eyes; Inhalation may cause spasm, edema of the larynx and bronchi, chemical pneumonitis, and pulmonary edema; [HSDB] A severe irritant in animal experiments; In subchronic inhalation studies, 50 ppm was the no-observable-effect level and 117 ppm produced eye and upper respiratory tract irritation; Caused anesthetic effects in lethal concentration studies; [OECD SIDS] See "ALDEHYDES."

Exposure Assessment
WEEL

25 ppm

Vapor Pressure

111 mm Hg

Odor Threshold Low

0.005 ppm

Odor Threshold High

9 ppm

Lethal Concentration

LC50 (rat) = 47,560 mg/m3/4hr

Explanatory Notes

Flash point = 20 deg F; Odor thresholds from AIHA; Odor recognition threshold = 0.039 ppm; [OECD SIDS]

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Toxic Pneumonitis

Yes

Neurotoxin

Other CNS Neurotoxin

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: