Agent Name

Neosolaniol

CAS Number

36519-25-2

Formula

C19-H26-O8

Major Category

Biological Agents

Synonyms

4-beta,15-Diacetoxy-3-alpha,8-alpha-dihydroxy-12,13-epoxytrichothec-9-ene; Neozolaniol; Solaniol (sesquiterpene); Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-, 4,15-diacetate; [ChemIDplus]

Category

Mycotoxins

Sources/Uses

A nonmacrocyclic trichothecene mycotoxin produced by Fusarium and other fungi; [Reference #1]

Comments

Trichothecenes often contaminate food and feed, and can cause alimentary hemorrhage and vomiting by ingestion; Skin contact may cause dermatitis; These mycotoxins are highly potent inhibitors of eukaryotic protein synthesis; [Reference #1] A mild skin irritant in guinea pigs, moderate skin irritant in rabbits, and severe skin irritant in rats; Causes stomach ulceration in lethal-dose studies of guinea pigs; Causes nucleated red blood cells in 5-week intermittent oral studies of rats; [RTECS]

Reference Link

PubMed Fulltext: Mycotoxins

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Other Information

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