Agent Name

Acetonylacetone

Alternative Name

2,5-Hexanedione

CAS Number

110-13-4

Formula

C6-H10-O2

Major Category

Solvents

Synonyms

1,2-Diacetylethane; 2,5-Diketohexane; 2,5-Hexadione; 2,5-Hexandione; Acetone, acetonyl-; Acetonyl acetone; Diacetonyl; HDO; alpha,beta-Diacetylethane; [ChemIDplus]

Category

Ketones (<C12)

Description

Liquid that slowly turns yellow; [Merck Index] Colorless to amber liquid with a sweet odor; [CAMEO] Yellow liquid; [Alfa Aesar MSDS]

Sources/Uses

Used as a solvent for cellulose acetate, roll-coating inks, lacquers, and stains; as an intermediate for pharmaceuticals and photographic chemicals; and in electroplating; [NTP]

Comments

A mild irritant; High concentrations may cause narcosis; [Merck Index] Causes degenerative changes to brain and nerves in 15-week intermittent dermal studies of rats; Causes neurotoxicity and male reproductive changes in repeated dose studies; [RTECS] A skin and strong eye irritant; Prolonged or repeated exposure may cause serious organ injury; May cause impaired fertility; Harmful by ingestion and inhalation; [Alfa Aesar MSDS]

Exposure Assessment
Vapor Pressure

2.93 mm Hg

Lethal Concentration

LC50 (rat) = 2,000 ppm/4hr

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: