Agent Name

Zinc arsenite

CAS Number

28837-97-0

Formula

As-H3-O3.3/2Zn

Major Category

Metals

Synonyms

Zinc arsenoate (2:3); Arsenous acid, zinc salt (2:3); [ChemIDplus] UN1712

Category

Arsenic Compounds, Inorganic

Description

Colorless solid soluble in acids, but insoluble in water; [Hawley]

Sources/Uses

Used as a timber preservative and an insecticide; [Hawley] No active pesticide product registrations in the US; [NPRIS]

Comments

Causes somnolence, dyspnea, and diarrhea in lethal-dose studies of rats and mice (dermal, intraperitoneal, and oral administration); Causes CNS effects, ulceration of stomach, and diffuse hepatitis in 20-day intermittent oral study of rats; [RTECS] See "Arsenic" and the linked occupational diseases.

Exposure Assessment
BEI

Inorganic arsenic plus methylated metabolites in urine = 35 ug As/L; end of workweek;

TLV (ACGIH)

0.01 mg/m3, as As

PEL (OSHA)

0.01 mg/m3, as As

MAK

0.1 mg/m3(respirable fraction), 2 mg/m3 (inhalable fraction) for Zn inorg. compds

IDLH (NIOSH)

5 mg/m3, as As

Adverse Effects
Anemia

Anemia, Aplastic

Neurotoxin

Sensorimotor Neuropathy

Hepatotoxin

Hepatotoxin, Secondary

Reproductive Toxin

Yes

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

ACGIH Carcinogen

Confirmed Human

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: