Agent Name

Hexamethoxydisilylethane

CAS Number

18406-41-2

Formula

C8-H22-O6-Si2

Major Category

Metals

Synonyms

Bis(trimethoxysilyl)ethane; 1,2-Bis(trimethoxysilyl)ethane; 1,2-Ethylenebis(trimethoxysilane); 1,4-Disilabutane, 1,1,1,4,4,4-hexamethoxy-; 3,3,6,6-Tetramethoxy-2,7-dioxa-3,6-disilaoctane; Dow Corning X1-6145A; 2,7-Dioxa-3,6-disilaoctane, 3,3,6,6-tetramethoxy-; [ChemIDplus]

Category

Metalloid Compounds (Silicon)

Description

Colorless liquid; [Aldrich MSDS]

Comments

Prolonged or repeated contact with the skin of rabbits causes marked to severe redness, mild swelling, and superficial necrosis; Acute and short-term inhalation studies of experimental animals demonstrate severe mucous membrane damage and epithelial necrosis of the cornea and respiratory tract at concentrations as low as 0.5 ppm; [ToxPlanet: EPA TSCATS] May cause irritation; May cause pneumonitis and pulmonary edema; May be fatal by inhalation; Targets the eye, kidney, liver, heart, and nerves; [Aldrich MSDS] Produces methanol on contact with moisture or water in the skin, eyes, and mucous membranes leading to irritation and dehydration of overexposed tissue; A severe eye irritant that may cause permanent injury including blindness; A pulmonary toxin that may cause lung injury from overexposure; [Gelest MSDS] See "Trimethoxysilane."

Exposure Assessment
Vapor Pressure

0.08 mm Hg

Lethal Concentration

LC50 (rat) = 2.4 ppm/4hr

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Other Information

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