Agent Name

Sesquiterpene lactones

Major Category

Biological Agents

Synonyms

Mum (Chrysanthemum indicum, C. morifolium); Liverwort (Frullania species); Ragweed and Feverfew (Ambrosia species); [Marks, p. 248-64]

Category

Plant-Derived Allergens

Sources/Uses

Allergic contact dermatitis in florists; [Marks]

Comments

"Sesquiterpene lactones are the allergens in chrysanthemums and other Compositae plants." Examples of these plants are broomweed, chamomile, chicory, cornflower, daisy, dandelion, feverfew, marigold, pyrethrum, ragweed, sunflower, thistle, and yarrow. Sesquiterpene lactones cause an acute or chronic dermatitis. Chronic dermatitis is more common, and it resembles a photodermatitis. Unlike a photodermatitis, the rash may involve the upper eyelids and the retroauricular and submental areas of the face. Florists and growers of chrysanthemums may present with rash of the fingers or hands. [Marks, p. 248-51] Danger of skin sensitization; [MAK]

Adverse Effects
Skin Sensitizer

Yes

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Diseases

Occupational diseases associated with exposure to this agent: