Agent Name

Malonaldehyde

CAS Number

542-78-9

Formula

C3-H4-O2

Major Category

Other Classes

Synonyms

1,3-Propanedial; 1,3-Propanedialdehyde; 1,3-Propanedione; Malondialdehyde; Malonic aldehyde; Malonic dialdehyde; Malonodialdehyde; Malonyldialdehyde; Propanedial; [ChemIDplus]

Category

Aldehydes

Description

Solid (needles); [NIOSH]

Sources/Uses

Used in scientific research; [HSDB] Produced during lipid peroxidation and other reactions in mammals; Used as index for rancidity in foods; [Merck Index] Found in many foods (at high levels if rancid); [IARC]

Comments

Evidence of injury to the liver and pancreas in mice experiments when added to drinking water at 500 mg/kg body weight per day; [HSDB] No listed effects of short-term or long-term exposure; [ICSC] May cause skin, eye, and respiratory tract irritation; Excessive exposure may cause CNS depression; [Merck Index] Causes muscle weakness, dyspnea, and cyanosis in oral lethal-dose study of rats; Causes other gastrointestinal and liver changes and inflammation, necrosis, or scarring of bladder in 90-day oral study of mice; [RTECS] See "ALDEHYDES"

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Other Information

No other related information on this agent was found.