Agent Name

2,7-Naphthalenediol

CAS Number

582-17-2

Formula

C10-H8-O2

Major Category

Other Classes

Synonyms

2,7-Dihydroxynaphthalene; C.I. 76645; CI 76645; Naphthalene-2,7-diol; Naphthalenediol-2,7 [French]; [ChemIDplus]

Category

Naphthols

Description

Light grey or slightly yellow solid; [ToxPlanet: EC: Opinion of the SCCP on 2,7-naphthalenediol] Grey powder; [Alfa Aesar MSDS]

Sources/Uses

Used in oxidative hair dye formulations; [ToxPlanet: EC: SCCP]

Comments

Not irritating to rabbit skin; Highly irritating and corrosive to rabbit eyes; A moderate skin sensitizer using the mouse local lymph node assay (LLNA); Changes in hematology (reduced hemoglobin in males and higher MCV and MCH values in females), clinical chemistry (increased GGT in males and ALT in females), and histopathological changes in liver and kidney observed in 90-day oral study of rats; Hematological changes and histopathology of liver and kidney reversed within four week recovery period; No evidence of teratogenicity in rats; Not likely to have mutagenic potential in vivo; [ToxPlanet: EC: SCCP] A skin and strong eye irritant; [Alfa Aesar MSDS] See "1-Napththol" and "2-Naphthol."

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
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Chemical Information

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