Agent Name

Thiourea

CAS Number

62-56-6

Formula

C-H4-N2-S

Major Category

Nitrogen Compounds

Synonyms

2-Thiopseudourea; 2-Thiourea; Isothiourea; Pseudothiourea; Pseudourea, 2-thio-; Sulourea; THU; Thiocarbamide; Thiocarbonic acid diamide; Thiomocovina [Czech]; Thiourea; Thiuronium; Tsizp 34; Urea, 2-thio-; Urea, thio-; beta-Thiopseudourea; Urea, 2-thio-; Urea, thio- (8CI); [ChemIDplus] UN2811

Category

Thiourea Compounds

Description

White or off-white crystals or powder; [CAMEO]

Sources/Uses

Used in compounds to clean silver and copper; also used in diazo copy paper; [Kanerva, p. 1839] Used in photography (toning solution); [www.ci.tucson.az.us/arthazards/medium.html]

Comments

Thiourea (thiocarbamide) has been used as a fixative in photography and photocopying. It has also been used as a rubber and neoprene antioxidant. Photocontact dermatitis caused by thiourea has been observed in users of shoe insoles, adhesive tape, wet suits, and neoprene weather strips. Alkylated thioureas include diethylthiourea (DTU), Diphenylthiourea (DPTU), Ethylenethiourea (ETU), Dimethylthiourea (DMTU), and ethylbutylthiourea (EBTU). [Marks, 239-40] Danger of skin sensitization and photo-contact sensitization; [MAK] See "Ethylene thiourea,"

Reference Link

Occupational allergic contact dermatitis caused by thiourea compounds

Exposure Assessment
Vapor Pressure

0.0028 mm Hg

Lethal Concentration

LC50 (rat) > 900 mg/m3/4h

Adverse Effects
Dermatotoxin

Contact Dermatitis, Photoallergic

IARC Carcinogen

Not Classifiable

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: