Agent Name

Nicotinic acid

Alternative Name


CAS Number




Major Category

Biological Agents


3-Carboxylpyridine; 3-Carboxypyridine; Acide nicotinique [INN-French]; Acido nicotinico [INN-Spanish]; Acidum nicotinicum [INN-Latin]; Akotin; Apelagrin; Bionic; Daskil; Davitamon PP; Diacin; Direktan; Efacin; Enduracin; Kyselina nikotinova [Czech]; Linic; NAH; NICO; Naotin; Niac; Niacin; Niacor; Niaspan; Niaspan Titration Starter Pack; Nicacid; Nicagin; Nicamin; Nicangin; Nico-400; Nico-Span; Nicobid; Nicocap; Nicocidin; Nicocrisina; Nicodan; Nicodelmine; Nicodon; Nicolar; Niconacid; Niconat; Niconazid; Nicorol; Nicosan 3; Nicoside; Nicosyl; Nicotamin; Nicotene; Nicotil; Nicotine acid; Nicotinipca; Nicotinsaure [German]; Nicovasan; Nicovasen; Nicyl; Nipellen; Nyclin; Pellagramin; Pellagrin; Pelonin; Peviton; Pyridine-3-carboxylic acid; Pyridine-beta-carboxylic acid; Pyridine-carboxylique-3 [French]; S115; SK-Niacin; SR 4390; Slo-niacin; Tega-Span; Tinic; Vitaplex N; Wampocap; 3-Pyridinecarboxylic acid; Pyridinecarboxylic acid, 3-; [ChemIDplus]


Vitamins and Derivatives


White solid; [ICSC] Colorless odorless solid; [HSDB] White powder; [Sigma-Aldrich MSDS]


Occurs naturally especially in liver, fish, yeast, and cereal grains; Used as a drug (antilipemic and vitamin); [Merck Index] Used in the chemical, agricultural, animal feed, and food industries, in cosmetics, pharmaceuticals, as a food additive, intermediate, and laboratory chemical; [IUCLID] Used as a medication, nutrient, in animal feeds, enriched flours, as a chemical intermediate, and in electroplating bathes; [HSDB] Used as a nutritional supplement; [FDA] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]


A mild eye irritant; [ICSC] Flushing of the skin accompanied by itching, tingling, and warmness have been observed following occupational exposure; [IUCLID] Ingestion of large amounts, e.g., by drug abusers attempting to mask drugs in the urine, can cause vomiting, abdominal pain, dizziness, and hypoglycemia followed by persistent hyperglycemia, acidosis, hypotension, and coagulopathy; Also, chronic, excessive use may cause hepatitis; [Olson, p. 445-6] May cause mild upper respiratory tract irritation; [NTP] An irritant that may cause severe eye irritation; [Sigma-Aldrich MSDS] See "Nicotinamide."

Exposure Assessment
Vapor Pressure

5.7E-6 mm Hg

Adverse Effects

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information


Chemical Information

Search ChemIDplus

Related Information in HazMap

Industrial Processes with risk of exposure: